Peptide Database

Peptide NameBrevinin-1-OR3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC105H164N32O29S4

DescriptionStandard

        PFVASVATEMMHHVYCAASRRC
    

Molecular Weight2466.88 Da

Isoelectric Point (pI)8.44

Net Charge (pH 7.0)1.11

Net Charge (pH 7.4) 0.92

Charge Density (pH 7.0) 0.0507

GRAVY Index0.33

Hydrophobic Moment 0.44

Boman Index0.10

Instability Index83.15

Aliphatic Index 57.73

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 959.81

LogP -9.70

H-bond Donors 38.0

H-bond Acceptors 36.0

Rotatable Bonds 76.0

Heavy Atoms 170.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207227 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)