Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length2 amino acids

Chemical FormulaC9H14N2O5

DescriptionStandard

DP

Molecular Weight230.22 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.44

Charge Density (pH 7.0) -0.6194

GRAVY Index-2.55

Hydrophobic Moment 0.46

Boman Index-0.39

Instability Index5.00

Aliphatic Index 0.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 120.93

LogP -1.14

H-bond Donors 3.0

H-bond Acceptors 4.0

Rotatable Bonds 4.0

Heavy Atoms 16.0

Ring Count 1.0

Amide Bonds 1.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229789 VERIFIED: NO

Provenance & Taxonomy

OrganismArthropoda [Animal]

Tax ID6656

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive

RECORD: Rec_0425833 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/

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