Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length506 amino acids

Chemical FormulaC2554H3953N637O731S20

DescriptionStandard

        MHTKAVQLLWGCFFLWNLYISSAQTVYPGIKARVTQQALDYGVLAGMEMIEQMVKEKKIPDLEGSESLEFLKVDYVNYNFSNIKIHAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEVKSPLFQDTGGADLFLSGVFFTGIIVLARNNFGHPIMKLQDCYAQVSHAHVSFSGDLSVLYNSFAEPMEKPILKNLNEMLCPMIMSEVGALNANLSMLEVLTKIDNYTLLDYSLISSPEITENYMELNLKGVFYPLDNLSDPPFSPVPFALPEHHDSMLYIGISEFFFKSASFAYFTAGAFNVTLSMKEISNHLVQNSQGLGNVLSRIAEIYLLSQPFMVQVMATEPPAISLQPGNFTLDIPASIVLLAQTENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESNRSNIEVLRFENILSSILHFGILPLANARLTHAVPLANPRGVTLSSFLPPFQGFLLISTDLKYETSLKQQPSFHGWEGLNLISGQWRGKPAA
    

Molecular Weight55918.83 Da

Isoelectric Point (pI)5.39

Net Charge (pH 7.0)-12.43

Net Charge (pH 7.4) -13.42

Charge Density (pH 7.0) -0.0246

GRAVY Index0.20

Hydrophobic Moment 0.63

Boman Index0.20

Instability Index36.92

Aliphatic Index 101.36

Aromaticity 0.1047

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 50100.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032139 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria

MethodQualitative functional evidence