Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC750H1174N220O217S5

DescriptionStandard

        MAKVQFKQRATTEAIFVHCSATKPSQNVGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDELAVGSHAKGYNHNSIGVCLVGGIDDKGKFDANFTPAQMQSLRSLLVTLLAKYEGSVLRAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16905.01 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)4.10

Net Charge (pH 7.4) 3.44

Charge Density (pH 7.0) 0.0271

GRAVY Index-0.45

Hydrophobic Moment 0.75

Boman Index-0.05

Instability Index39.49

Aliphatic Index 77.48

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7061.97

LogP -70.89

H-bond Donors 249.0

H-bond Acceptors 233.0

Rotatable Bonds 566.0

Heavy Atoms 1192.0

Ring Count 28.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0097690 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage Patroon [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic