Peptide Database

Peptide NameBeta-defensin 119 (Beta-defensin 120) (Defensin; beta 119) (Defensin; beta 120)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC439H692N122O118S9

DescriptionStandard

        MKFLFLFLAILLATKIPVISGKRHNLRCMGNSGICRASCKKNEQPYLYCRNYQACCLQSYMRISISGKEENTDWSYEKQWPRLP
    

Molecular Weight9855.52 Da

Isoelectric Point (pI)9.44

Net Charge (pH 7.0)7.53

Net Charge (pH 7.4) 7.15

Charge Density (pH 7.0) 0.0896

GRAVY Index-0.33

Hydrophobic Moment 0.49

Boman Index-0.06

Instability Index61.32

Aliphatic Index 77.86

Aromaticity 0.1190

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18825.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3914.79

LogP -34.10

H-bond Donors 143.0

H-bond Acceptors 136.0

Rotatable Bonds 328.0

Heavy Atoms 688.0

Ring Count 17.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011358 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyBeta-defensin; Defensin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic