Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC988H1565N267O265S10

DescriptionStandard

        PKAPPMAHEPMLLLAVTEIVANSAAFTYFTAGALRRNFSSDMLPRQFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLGGTVRLTGLVPDPQLTWTPLPVLCQAKDLPVPQVKRLETLLKFGLWLFGVPRANSKCCPCPVP
    

Molecular Weight21744.28 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)6.28

Net Charge (pH 7.4) 5.91

Charge Density (pH 7.0) 0.0320

GRAVY Index0.00

Hydrophobic Moment 0.55

Boman Index0.09

Instability Index51.23

Aliphatic Index 93.06

Aromaticity 0.0765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8331.87

LogP -101.30

H-bond Donors 284.0

H-bond Acceptors 285.0

Rotatable Bonds 680.0

Heavy Atoms 1530.0

Ring Count 46.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024511 VERIFIED: NO

Provenance & Taxonomy

OrganismAlaudala cheleensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria