Peptide Database

Peptide NameKlebicin B (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length773 amino acids

Chemical FormulaC3465H5565N1031O1139S15

DescriptionStandard

        MIGGFNYNGEGATSSGLSSPSASDVANQFNSFGGTQIRASDVSNIRSDGNGGYMADIRGQIHTVSSEEGSTTVSGFDGVRSSSTGNGGSQGGQGPQGQSLVMHNGQMGYWENRSSGAGNNEHTTRAFVAVGPSEAEKAARAEKVAKEKQQAEEAAKAFAAKTAAASAAAEKERQNAISAAAAAGQHQTVPDARNNLNQATAEASRLKTVADNALNTAKNKRKEAIDAVPVATQAEKKYQDLQQSIKGLTLNNNGQYGTQKWEVISSNKEHDHWGYRFYPSGITKAQVDAEQNDAVNKRNAATSLASQATAAEQASLQASAAYNAAETRRQAAQAALASAEQAAAAERKRQEAEAAAAAAAEKKRQADAAAKAAEEARAIAEKAKALQARCTAADKLKSSEIQAVRGIPATAAPFAIPLTWSTASRGGFTLSADAAASLGAFISEALATLSIAVVANPVALTIVGLVLSKSVGVGSDMVPGRDISSMMPGDAFGLPDTAALNKAADQKTSVSMPVRGRLVMNDSGILDVQLVKTNTAGAVKVARAVLDKETGYWGYTLPAVADVPAQTIFVSPADALGANGPLTLSGPVPLPERILHTGDQISAPQATDKTVTPVADDLDFDDIILVFPPESGLKPLYVMYRSPRNMPGTVSGKGQNVGNNWMGGASTGDGAPVPSQIADKLRGKTFGSFDSTRRAFWKAVADDSALSKQFSEADINQMKAGRAPTADFLESVGKRVKIELHHEKEISQGGAVMDVDNIKALTPKNHIETHKGK
    

Molecular Weight80371.45 Da

Isoelectric Point (pI)7.20

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) 0.0007

GRAVY Index-0.38

Hydrophobic Moment 0.63

Boman Index-0.01

Instability Index38.49

Aliphatic Index 72.30

Aromaticity 0.0492

Extinction Coeff. Reduced 56380.00

Extinction Coeff. Oxidized 56380.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0241602 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence