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MYP_131874
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Basic Information
Cecropin A (1-7)-melittin (1-8)hybrid peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
15 amino acids
C85H143N21O16
Standard
Sequence
KWKLFKKGIGAVLKV
Physicochemical Analysis
1715.18 Da
10.60
4.76
4.54
0.3170
0.26
0.59
0.12
-34.65
123.33
0.1333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
616.61
-0.47
22.0
21.0
61.0
122.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305475 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli D21
4 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0308918 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
sheep red cells
300 μM
Hemolysis
PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
RECORD: Rec_0329095 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperCAMP: Collection of sequences and structures of antimicrobial peptides (https://pubmed.ncbi.nlm.nih.gov/24265220/) PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0371830 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa OT97
15 μM
MIC
PaperPubMed PMID: 1733777 PMID1733777 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1733777/
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