Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length178 amino acids

Chemical FormulaC875H1397N241O236S7

DescriptionStandard

        PAALPVAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSSMLPRRFPLQLRTKSVGLFCPELQERYPDQPMELHLSARQQPLLSCRPDALHGALFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTITGNRLGGTVSLRGGLLPVPQVKRLETLLKFGLWLFGVPRANSECCPPPVP
    

Molecular Weight19293.38 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)6.20

Net Charge (pH 7.4) 5.91

Charge Density (pH 7.0) 0.0348

GRAVY Index0.16

Hydrophobic Moment 0.57

Boman Index0.12

Instability Index61.83

Aliphatic Index 99.21

Aromaticity 0.0730

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7459.16

LogP -80.73

H-bond Donors 257.0

H-bond Acceptors 252.0

Rotatable Bonds 606.0

Heavy Atoms 1359.0

Ring Count 37.0

Amide Bonds 190.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0080433 VERIFIED: NO

Provenance & Taxonomy

OrganismPelecanoides urinatrix (Common diving petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria