Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC409H639N109O129S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSAVPFTKVQELEEPMSNDGAVAAAEEMSEDTWKMPYNNRHKRSPADCRFCCGCCPDMTGCGVCCTF
    

Molecular Weight9596.01 Da

Isoelectric Point (pI)4.75

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.90

Charge Density (pH 7.0) -0.0509

GRAVY Index0.08

Hydrophobic Moment 0.40

Boman Index0.08

Instability Index83.11

Aliphatic Index 57.61

Aromaticity 0.0795

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3774.06

LogP -41.46

H-bond Donors 137.0

H-bond Acceptors 140.0

Rotatable Bonds 308.0

Heavy Atoms 661.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156124 VERIFIED: NO

Provenance & Taxonomy

OrganismSparus aurata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal