Peptide Database

Peptide NameCAP3720-44ser26/42

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral assembly inhibition ▸ Assembly inhibitor

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC118H180N38O33S

DescriptionStandard

        NQGRHFSGGALIHARFVMTAASSFQ
    

Molecular Weight2690.99 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.63

Charge Density (pH 7.0) 0.0774

GRAVY Index-0.01

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index23.17

Aliphatic Index 58.80

Aromaticity 0.1200

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1153.07

LogP -14.54

H-bond Donors 41.0

H-bond Acceptors 38.0

Rotatable Bonds 87.0

Heavy Atoms 190.0

Ring Count 5.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0000150 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHost-derived peptide

Tax ID9606;0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral Assembly inhibitor

TargetAdenovirus 5 (Assembly); A549

MethodDirect time kill assay

PaperCAP37-derived antimicrobial peptides have in vitro antiviral activity against adenovirus and herpes simplex virus type 1. | Gordon YJ, Romanowski EG, Shanks RM, Yates KA, Hinsley H, Pereira HA. | Curr Eye Res. 2009 | PMID:19274533 PMID19274533 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19274533/

RECORD: Rec_0032222 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0290345 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0344692 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial