Peptide Database

Peptide NameMolluscan insulin-related peptide 1 A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC115H190N32O38S6

DescriptionStandard

        QGTTNIVCECCMKPCTLSELRQYCP
    

Molecular Weight2821.32 Da

Isoelectric Point (pI)6.11

Net Charge (pH 7.0)-0.29

Net Charge (pH 7.4) -0.57

Charge Density (pH 7.0) -0.0114

GRAVY Index-0.12

Hydrophobic Moment 0.31

Boman Index-0.03

Instability Index79.80

Aliphatic Index 58.40

Aromaticity 0.0400

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1137.08

LogP -13.52

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 90.0

Heavy Atoms 191.0

Ring Count 3.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055493 VERIFIED: YES

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyMolluscan insulin-related peptide

Tax ID6523

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Disulfide10-15

Bio-Activity Profile

Function

Hormone Endocrine

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0079304 VERIFIED: YES

Provenance & Taxonomy

OrganismLymnaea stagnalis [Animal]

FamilyInsulin

Tax ID6523

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0326151 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/