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MYP_131598
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Basic Information
Japonicin-2LF
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C112H184N24O22S2
Standard
Sequence
FIVPSIFLLKKAFCIALKKC
Physicochemical Analysis
2282.94 Da
9.70
3.74
3.50
0.1868
1.41
0.50
0.39
16.02
141.50
0.1500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
731.74
0.18
27.0
28.0
76.0
160.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0124239 VERIFIED: NO
Provenance & Taxonomy
Limnonectes fujianensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0129102 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus NCTC 10788 or MRSA NCTC 12493
4 μM
MIC
PaperA novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
RECORD: Rec_0138033 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0157177 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
>512 μM
MIC
PaperA novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
RECORD: Rec_0195146 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli NCTC 10418
16 μM
MIC
PaperA novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
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