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MYP_131598
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Basic Information
Japonicin-2LF
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxicity
Standard
20 amino acids
C112H184N24O22S2
Standard
Sequence
FIVPSIFLLKKAFCIALKKC
Physicochemical Analysis
2282.94 Da
9.70
3.74
3.50
0.1868
1.41
0.50
0.39
16.02
141.50
0.1500
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
731.74
0.18
27.0
28.0
76.0
160.0
4.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0043154 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal
MRSA B038 V1S1 A
8 μM
MIC
PaperA novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
RECORD: Rec_0076026 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fujianensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans NCYC 1467
4 μM
MIC
PMID30802593 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30802593/
RECORD: Rec_0105422 VERIFIED: YES
Provenance & Taxonomy
Limnonectes fujianensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
64 μM
Hemolysis
PMID30802593 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30802593/
RECORD: Rec_0111214 VERIFIED: YES
Provenance & Taxonomy
Galleria mellonella [Animal]
7137
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
14-20
Bio-Activity Profile
Antimicrobial Antifungal Toxicity
MODERATE hemolytic
32-64 μM
HC50
PaperA novel membrane-disruptive antimicrobial peptide from frog skin secretion against cystic fibrosis isolates and evaluation of anti-MRSA effect using Galleria mellonella model
RECORD: Rec_0111962 VERIFIED: YES
Provenance & Taxonomy
Animalia [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID30802593 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30802593/
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