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MYP_131593
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Basic Information
Mel(12-26, L4)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C85H146N26O19
Standard
Sequence
GLPLLISWIKRKRQQ
Physicochemical Analysis
1836.23 Da
12.00
3.76
3.55
0.2505
-0.47
0.54
-0.17
85.66
130.00
0.0667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
759.97
-4.41
27.0
23.0
63.0
130.0
3.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008170 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
2.4 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0044549 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
76.7 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0177150 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
1.3 μg/mL
MIC
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0205935 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
human erythrocytes
1300 μg/mL
Hemolysis
PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
RECORD: Rec_0370347 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
Human erythrocytes
203 μg/mL
Paperhttps://pubmed.ncbi.nlm.nih.gov/14596922/ PMID14596922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14596922/
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