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MYP_131589
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Basic Information
Phoratoxin (Plant defensin)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
46 amino acids
C203H329N65O63S6
Standard
Sequence
KSCCPTTTARNIYNTCRFGGGSRPVCAKLSGCKIISGTKCDSGWNH
Physicochemical Analysis
4880.57 Da
9.34
5.78
5.43
0.1257
-0.41
0.64
-0.08
57.57
44.57
0.0652
6990.00
7365.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2078.59
-30.37
81.0
76.0
158.0
337.0
7.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029418 VERIFIED: YES
Provenance & Taxonomy
Phoradendron tomentosum [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Cytotoxic
PaperPubMed PMID: 4606908 PMID4606908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4606908/
RECORD: Rec_0051607 VERIFIED: NO
Provenance & Taxonomy
Phoradendron tomentosum [Plant]
Thionin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://www.uniprot.org/uniprotkb/P01539/entry
RECORD: Rec_0105730 VERIFIED: NO
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0215656 VERIFIED: YES
Provenance & Taxonomy
California mistletoe [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
PaperPhoratoxin, a toxic protein from the mistletoe Phoradendron tomentosum subsp. macrophyllum (Loranthaceae). The disulphide bonds.
RECORD: Rec_0301727 VERIFIED: YES
Provenance & Taxonomy
Phoradendron tomentosum [Plant]
Thionin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Toxin
PMID4415051;4606908 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/4415051/
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