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MYP_131587
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Basic Information
Insulin A chain
Anticancer
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
21 amino acids
C99H155N25O35S4
Standard
Sequence
GIVEQCCTSICSLYQLENYCN
Physicochemical Analysis
2383.70 Da
4.05
-2.28
-2.54
-0.1084
0.21
0.41
0.14
22.54
88.10
0.0952
2980.00
3230.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
993.43
-11.44
37.0
37.0
77.0
163.0
2.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0297287 VERIFIED: NO
Provenance & Taxonomy
Pongo pygmaeus [Animal]
Insulin
9600
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-11
Bio-Activity Profile
Hormone Endocrine Metabolic regulation Physiological regulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0299103 VERIFIED: YES
Provenance & Taxonomy
Pan troglodytes [Animal]
Insulin
9598
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID14426955 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14426955/
RECORD: Rec_0306533 VERIFIED: YES
Provenance & Taxonomy
Physeter catodon [Animal]
Insulin
9755
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID13373434 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/13373434/
RECORD: Rec_0307074 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Insulin
9606
Structure & Mods
linear peptide/protein therapeutic [Linear]
canonical L-amino-acid peptide [L]
Lipidation
Bio-Activity Profile
Hormone replacement
approximately 25 hours
Evidence URLhttps://webs.iiitd.edu.in/raghava/thpdb2/display_thppid.php?details=Th1213
RECORD: Rec_0327813 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
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