Peptide Database

Peptide NameA. dichotoma defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length42 amino acids

Chemical FormulaC193H318N64O53S6

DescriptionStandard

        VTCDLLSFSSKIFSFNHSACAAHCLAKRKKGGRCVNGVCRCR
    

Molecular Weight4575.38 Da

Isoelectric Point (pI)9.61

Net Charge (pH 7.0)6.85

Net Charge (pH 7.4) 6.44

Charge Density (pH 7.0) 0.1630

GRAVY Index0.06

Hydrophobic Moment 0.75

Boman Index-0.08

Instability Index31.22

Aliphatic Index 67.38

Aromaticity 0.0714

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1910.32

LogP -24.22

H-bond Donors 76.0

H-bond Acceptors 68.0

Rotatable Bonds 154.0

Heavy Atoms 316.0

Ring Count 5.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0088865 VERIFIED: YES

Provenance & Taxonomy

OrganismThermobia domestica [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)