Peptide Database

Peptide NameSLAY-screened peptide P4772

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC17H23N3O5

DescriptionStandard

FSP

Molecular Weight349.38 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0800

GRAVY Index0.13

Hydrophobic Moment 0.38

Boman Index0.38

Instability Index153.13

Aliphatic Index 0.00

Aromaticity 0.3333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 132.96

LogP -0.89

H-bond Donors 4.0

H-bond Acceptors 5.0

Rotatable Bonds 7.0

Heavy Atoms 25.0

Ring Count 2.0

Amide Bonds 2.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225638 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/