Peptide Database

Peptide NameIL-36α

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length158 amino acids

Chemical FormulaC788H1252N210O233S9

DescriptionStandard

        MEKALKIDTPQQGSIQDINHRVWVLQDQTLIAVPRKDRMSPVTIALISCRHVETLEKDRGNPIYLGLNGLNLCLMCAKVGDQPTLQLKEKDIMDLYNQPEPVKSFLFYHSQSGRNSTFESVAFPGWFIAVSSEGGCPLILTQELGKANTTDFGLTMLF
    

Molecular Weight17684.22 Da

Isoelectric Point (pI)5.89

Net Charge (pH 7.0)-2.26

Net Charge (pH 7.4) -2.72

Charge Density (pH 7.0) -0.0143

GRAVY Index-0.15

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index44.88

Aliphatic Index 92.53

Aromaticity 0.0759

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7108.03

LogP -66.79

H-bond Donors 243.0

H-bond Acceptors 243.0

Rotatable Bonds 588.0

Heavy Atoms 1240.0

Ring Count 26.0

Amide Bonds 174.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0220789 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsTyrosine residue at position 96 is nitrated.

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-36 receptor (Human)