Peptide Database

Peptide NameAlpha-purothionin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC110H189N33O29S4

DescriptionStandard

        AQKLCAGVCRCKIASGLSCPKGFPK
    

Molecular Weight2566.14 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)4.75

Net Charge (pH 7.4) 4.50

Charge Density (pH 7.0) 0.1901

GRAVY Index0.20

Hydrophobic Moment 0.55

Boman Index0.03

Instability Index27.86

Aliphatic Index 70.40

Aromaticity 0.0400

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 250.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 993.67

LogP -11.21

H-bond Donors 38.0

H-bond Acceptors 38.0

Rotatable Bonds 85.0

Heavy Atoms 176.0

Ring Count 3.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0170770 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)