Peptide Database

Peptide NameMouse beta-defensin-14

Function Ontology

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Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC191H335N69O52S6

DescriptionStandard

        AAQKYHCKLRRGRCAVLGCLPKEEQIGSCSLSGRKCCRRKK
    

Molecular Weight4622.52 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)9.82

Net Charge (pH 7.4) 9.48

Charge Density (pH 7.0) 0.2396

GRAVY Index-0.74

Hydrophobic Moment 0.57

Boman Index-0.38

Instability Index71.26

Aliphatic Index 61.95

Aromaticity 0.0244

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2016.43

LogP -24.15

H-bond Donors 80.0

H-bond Acceptors 69.0

Rotatable Bonds 164.0

Heavy Atoms 318.0

Ring Count 3.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024937 VERIFIED: YES

Provenance & Taxonomy

OrganismOchotona princeps [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)