Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC615H960N164O171S15

DescriptionStandard

        MKILLSFSILSFGVFIPPVGCDQPITNSMPLLMTICRKRFEKLYSEMHNYSTIFEKAKYGTKENNPARSKEHYAVFNWWEACIKLSGQCKNQCGEKEFKMAYCARPTTLCCMRQCDRIE
    

Molecular Weight13868.17 Da

Isoelectric Point (pI)8.88

Net Charge (pH 7.0)5.60

Net Charge (pH 7.4) 5.11

Charge Density (pH 7.0) 0.0471

GRAVY Index-0.31

Hydrophobic Moment 0.58

Boman Index-0.03

Instability Index50.04

Aliphatic Index 64.79

Aromaticity 0.1176

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18950.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5416.51

LogP -47.40

H-bond Donors 196.0

H-bond Acceptors 194.0

Rotatable Bonds 462.0

Heavy Atoms 965.0

Ring Count 24.0

Amide Bonds 128.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0043900 VERIFIED: NO

Provenance & Taxonomy

OrganismOdobenus rosmarus divergens [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence