Peptide Database

Peptide Namebempegaldesleukin

Function Ontology

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length132 amino acids

Chemical FormulaC690H1115N177O203S6

DescriptionStandard

        PTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFSQSIISTLT
    

Molecular Weight15330.69 Da

Isoelectric Point (pI)7.31

Net Charge (pH 7.0)0.22

Net Charge (pH 7.4) -0.06

Charge Density (pH 7.0) 0.0017

GRAVY Index-0.21

Hydrophobic Moment 0.66

Boman Index0.02

Instability Index53.65

Aliphatic Index 103.41

Aromaticity 0.0758

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10095.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6173.52

LogP -52.83

H-bond Donors 213.0

H-bond Acceptors 212.0

Rotatable Bonds 525.0

Heavy Atoms 1076.0

Ring Count 19.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0389781 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidereported in GtoPdb PTM annotation

Other ModsDisulphide bond between cysteine residues at positions 57 and 104.

Bio-Activity Profile

Function

Receptor agonist Immunomodulatory Signaling peptide

TargetInterleukin-2 receptor subunit β (Human)

Activity1769 nM

MethodKd