Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length482 amino acids

Chemical FormulaC2397H3826N648O668S19

DescriptionStandard

        MARDQDSTRTWAALVVLATAGTALAAAANPGFVIRISQAGLDYVRQQEMPMLQKKLESIKLPDFSGSFKMSFLGKGHYSFYSMNVLNFQLPSSQIRLQPNVGLQLSIGNAHVTINGKWKARKKFLKLRGSFVLRVEGVSISADLKLGRDPPSGRFTVACSSCSSSINRVHLSSRGIVGWLLRLFHKKVDSMLRKLLNKNICKILSNSVANDLQQYINTVPVTSKIDKVSAINYSLVASPIVTANSLDLPLKGEFFSQASRSPPPFEPPVIAIPPDHDRMVYLAMSDYFFNTAGLVYQRAGVLKWSLTNNTLPKGSKFQLTTNFLGEFLPQVSQKFPNMDVKLVLSASSPPHLVMQPTGLTLASTLEAQAFAVHPNSSLASLFLLGMNITAHMEVGANADRLTGEFMMDTLHLKLIHSNIGTFPVELLQSIMNYILPSVVLPKINKRLQRGFPLPVPNGVQLSNLVFRSYQDFLLLGADVRCG
    

Molecular Weight53019.19 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)21.34

Net Charge (pH 7.4) 20.48

Charge Density (pH 7.0) 0.0443

GRAVY Index0.08

Hydrophobic Moment 0.78

Boman Index0.11

Instability Index40.78

Aliphatic Index 99.71

Aromaticity 0.0830

Extinction Coeff. Reduced 36900.00

Extinction Coeff. Oxidized 37150.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0048883 VERIFIED: NO

Provenance & Taxonomy

OrganismOctodon degus (Degu) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria