Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC232H387N65O78S6

DescriptionStandard

        MKQSDEMLELIQEVSLDELDQVIGGAGNGVIRTITQGCRMPNNMQVLFTC
    

Molecular Weight5527.33 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-4.51

Net Charge (pH 7.4) -4.76

Charge Density (pH 7.0) -0.0901

GRAVY Index-0.03

Hydrophobic Moment 0.78

Boman Index0.07

Instability Index25.99

Aliphatic Index 95.40

Aromaticity 0.0200

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2337.22

LogP -25.39

H-bond Donors 79.0

H-bond Acceptors 80.0

Rotatable Bonds 192.0

Heavy Atoms 381.0

Ring Count 2.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345002 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence