Peptide Database

Peptide NameSLAY-screened peptide P4857

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC22H39N9O8

DescriptionStandard

        RAQPS
    

Molecular Weight557.60 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)0.76

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.1520

GRAVY Index-1.72

Hydrophobic Moment 0.41

Boman Index-0.56

Instability Index85.04

Aliphatic Index 20.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 296.15

LogP -4.62

H-bond Donors 10.0

H-bond Acceptors 9.0

Rotatable Bonds 16.0

Heavy Atoms 39.0

Ring Count 1.0

Amide Bonds 5.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0250125 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/