Peptide Database

Peptide NameBrevinin-2KK3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC377H621N97O114S5

DescriptionStandard

        MFTTKKPMLLFFFLGTISLSLCQEEERGADEDEVVEEEVKRGLLSVFKGVLKTAGKNVAKNVAGSLLDQLKCKISGGC
    

Molecular Weight8496.87 Da

Isoelectric Point (pI)6.23

Net Charge (pH 7.0)-0.51

Net Charge (pH 7.4) -0.80

Charge Density (pH 7.0) -0.0066

GRAVY Index0.06

Hydrophobic Moment 0.65

Boman Index0.06

Instability Index21.21

Aliphatic Index 96.15

Aromaticity 0.0641

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3417.94

LogP -31.14

H-bond Donors 120.0

H-bond Acceptors 119.0

Rotatable Bonds 299.0

Heavy Atoms 593.0

Ring Count 6.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237247 VERIFIED: NO

Provenance & Taxonomy

OrganismRana kukunoris [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence