Peptide Database

Peptide NameBrevinin-1-OR3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC104H162N30O28S4

DescriptionStandard

        PFVASVAAEMMHHVYCAASKRC
    

Molecular Weight2408.84 Da

Isoelectric Point (pI)8.42

Net Charge (pH 7.0)1.11

Net Charge (pH 7.4) 0.92

Charge Density (pH 7.0) 0.0506

GRAVY Index0.47

Hydrophobic Moment 0.37

Boman Index0.17

Instability Index54.42

Aliphatic Index 62.27

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 903.70

LogP -8.20

H-bond Donors 35.0

H-bond Acceptors 35.0

Rotatable Bonds 75.0

Heavy Atoms 166.0

Ring Count 5.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0299706 VERIFIED: YES

Provenance & Taxonomy

OrganismPelophylax nigromaculatus [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)