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MYP_131247
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Basic Information
HBD3 [C11,18,23,33,40,41S]
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
45 amino acids
C216H377N75O65
Standard
Sequence
GIINTLQKYYSRVRGGRSAVLSSLPKEEQIGKSSTRGRKSSRRKK
Physicochemical Analysis
5064.77 Da
11.65
10.76
10.54
0.2391
-1.14
0.65
-0.42
72.77
67.11
0.0444
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2370.98
-31.65
89.0
76.0
182.0
356.0
3.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0082732 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Burkholderia cepacia WaaC::kann
25 μg/mL
MBC
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0085414 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 2010/0048469 A1 Evidence URLhttps://patents.google.com/patent/US20100048469A1/en PatentUS 2010/0048469 A1
RECORD: Rec_0089859 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 8.9%, E 20.0%, T 33.3%, C 37.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Antimicrobial Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0101908 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli WBB 01
0.78 μg/mL
MBC
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
RECORD: Rec_0162286 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
4.7 μg/mL
LC50
PMID18350527 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18350527/
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