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MYP_131246
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Basic Information
Rice defensin OsAFP1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
49 amino acids
C227H366N76O69S9
Standard
Sequence
RHCLSQSHRFKGMCVSSNNCANVCRTESFPDGECKSHGLERKCFCKKVC
Physicochemical Analysis
5552.39 Da
8.92
4.95
4.46
0.1010
-0.63
0.43
-0.25
41.39
35.71
0.0612
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2378.24
-32.04
92.0
86.0
189.0
381.0
7.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0184436 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Saccharomyces cerevisiae S288C
16 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0199130 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
63 μg/mL
MIC
RECORD: Rec_0206429 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Porphyromonas gingivalis ATCC 33277
32 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0209657 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
4530
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
15 μg/mL
MIC
RECORD: Rec_0217274 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Saccharomyces cerevisiae BY4742
4 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
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