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MYP_131246
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Basic Information
Rice defensin OsAFP1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
49 amino acids
C227H366N76O69S9
Standard
Sequence
RHCLSQSHRFKGMCVSSNNCANVCRTESFPDGECKSHGLERKCFCKKVC
Physicochemical Analysis
5552.39 Da
8.92
4.95
4.46
0.1010
-0.63
0.43
-0.25
41.39
35.71
0.0612
0.00
500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2378.24
-32.04
92.0
86.0
189.0
381.0
7.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001035 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus subsp. aureus NBRC 12732
32 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0023633 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli K-12
32 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0039365 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus mutans JCM 5705
32 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0060401 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa Japonica Group [Plant]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans CAI4
4 μM
MIC
PMID30061724 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30061724/
RECORD: Rec_0066824 VERIFIED: YES
Provenance & Taxonomy
Oryza sativa [Plant]
Defensin
4530
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
multiple disulfide bonds reported, sites not specified
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Enzyme inhibitory ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
PaperPubMed PMID 27527801 | Weerawanich et al., 2018 PMID27527801 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27527801/
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