Peptide Database

Peptide NameM-myrmeciitoxin-Mb1a (M-MIITX-Mb1a) (Pilosulin-3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC340H580N86O99S4

DescriptionStandard

        MKLSCLLLTLAIIVVLTIVHAPNVEAKALADPESDAVGFADAVGEADPNAIIGLVSKGTCVLVKTVCKKVLKQG
    

Molecular Weight7585.02 Da

Isoelectric Point (pI)6.52

Net Charge (pH 7.0)-0.44

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0059

GRAVY Index0.80

Hydrophobic Moment 0.63

Boman Index0.29

Instability Index11.43

Aliphatic Index 135.68

Aromaticity 0.0135

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2904.05

LogP -23.77

H-bond Donors 100.0

H-bond Acceptors 104.0

Rotatable Bonds 254.0

Heavy Atoms 529.0

Ring Count 5.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0412648 VERIFIED: YES

Provenance & Taxonomy

OrganismMyrmecia banksi [Animal]

FamilyFormicidae venom precursor-01; Ant pilosulin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Yeast Cytolytic Hemolytic