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MYP_131189
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Basic Information
Ltc5_M6R
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
28 amino acids
C165H256N48O34
Standard
Sequence
GFFGKRKEYFKKFGASFKRRFANLKKRL
Physicochemical Analysis
3456.10 Da
11.62
9.75
9.54
0.3484
-0.99
0.68
-0.36
45.20
35.00
0.2500
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1399.61
-9.39
52.0
44.0
123.0
247.0
7.0
28.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0094928 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Cytotoxic
Human erythrocytes
36 μM
EC50
Paperhttps://pubmed.ncbi.nlm.nih.gov/19563807/ PMID19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19563807/
RECORD: Rec_0131713 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
1.5 μM
MIC
PMID19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19563807/
RECORD: Rec_0163152 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes: >36 μM
50 %
Hemolysis
PaperPubMed PMID: 19563807 PMID19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19563807/
RECORD: Rec_0189273 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 19563807 PMID19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19563807/
RECORD: Rec_0273226 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Latarcin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis
0.7 μM
MIC
PMID19563807 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19563807/
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