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MYP_131160
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Basic Information
Temporin-CDYb, Temporin-1CEb
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
12 amino acids
C60H108N12O14
Standard
Sequence
ILPILSLIGGLL
Physicochemical Analysis
1221.57 Da
5.53
-0.24
-0.44
-0.0200
2.44
0.33
0.86
67.60
260.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
394.86
0.86
13.0
14.0
39.0
86.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066458 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100.0 μM
MIC
PaperLi-Li Jin et al. / Comparative Biochemistry and Physiology, Part B 154 (2009) 174-178. Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii PMID19539775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19539775/
RECORD: Rec_0095202 VERIFIED: YES
Provenance & Taxonomy
Rana amurensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Fusobacterium nucleatum CGMCC 1.2526
100 μM
MBC
PMID25056289;22348663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25056289/
RECORD: Rec_0110058 VERIFIED: YES
Provenance & Taxonomy
Rana amurensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human cervical carcinoma HeLa
112 μM
IC50
PMID25056289;22348663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25056289/
RECORD: Rec_0115611 VERIFIED: YES
Provenance & Taxonomy
Rana amurensis [Animal]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterobacter cloacae CGMCC 1.58
250 μM
MIC
PMID25056289;22348663 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25056289/
RECORD: Rec_0116920 VERIFIED: YES
Provenance & Taxonomy
Rana dybowskii [Animal]
Temporin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperLi-Li Jin et al. / Comparative Biochemistry and Physiology, Part B 154 (2009) 174-178. Characterization of antimicrobial peptides isolated from the skin of the Chinese frog, Rana dybowskii PMID19539775 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19539775/
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