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MYP_131139
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Basic Information
Antimicrobial peptide 2 (Cn-AMP2)
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
11 amino acids
C59H83N11O18S
Standard
Sequence
TESYFVFSVGM
Physicochemical Analysis
1266.42 Da
4.05
-1.60
-1.79
-0.1455
0.76
0.04
0.43
36.39
52.73
0.2727
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
472.54
-3.39
17.0
18.0
38.0
89.0
3.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0219375 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Xanthomonas arboricola pv. Pruni
12.5-25 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0226852 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Erwinia amylovora
50 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0250219 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Pseudomonas aeruginosa
PMID19111587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19111587/
RECORD: Rec_0271121 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0275651 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
170000 μg/mL
MIC
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