‹ ›
MYP_131117
← PREVIOUS NEXT → BACK
Basic Information
Mag(i +4)11
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
23 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GIGKFLHSAKKXGKAXVGEIXNS
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0018270 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 12,16; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa
8.84 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0079165 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 12,16; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
12.50 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0138646 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 12,16; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus
5.26 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0233093 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 12,16; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Hemolytic
human red blood cells
25 μg/mL
Hemolysis
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
RECORD: Rec_0283743 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
S5 stapling amino acid at 12,16; norleucine at 21; S5 stapling amino acid; norleucine; Hydrocarbon staple / ring-closing metathesis constraint
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
3.13 μg/mL
MIC
PMID31427820 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31427820/
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2