Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length79 amino acids

Chemical FormulaC393H651N115O106S9

DescriptionStandard

        MSGAMRIFFLISAALILLVHIFSARGGIYREMQCQKLDGRCEVECLSFEVKIGGCRAELTPLCCRKKRNKQKPSNSYKK
    

Molecular Weight8971.66 Da

Isoelectric Point (pI)9.65

Net Charge (pH 7.0)8.53

Net Charge (pH 7.4) 8.16

Charge Density (pH 7.0) 0.1080

GRAVY Index-0.09

Hydrophobic Moment 0.43

Boman Index-0.06

Instability Index36.03

Aliphatic Index 86.46

Aromaticity 0.0759

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3607.00

LogP -33.05

H-bond Donors 134.0

H-bond Acceptors 125.0

Rotatable Bonds 312.0

Heavy Atoms 623.0

Ring Count 9.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0246108 VERIFIED: NO

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyDefensin

Tax ID9713

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence