Peptide Database

Peptide NameDefensin (Galiomicin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC340H530N94O102S8

DescriptionStandard

        MAKNFQSVLLLVCLSFLVIVSSPQNAVQADTLIGSCVWGATNYTSDCNAECKRRGYKGGHCGSFLNVNCWCE
    

Molecular Weight7822.93 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.53

Net Charge (pH 7.4) 0.14

Charge Density (pH 7.0) 0.0073

GRAVY Index0.23

Hydrophobic Moment 0.55

Boman Index0.14

Instability Index42.52

Aliphatic Index 83.89

Aromaticity 0.0972

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3162.52

LogP -35.75

H-bond Donors 116.0

H-bond Acceptors 112.0

Rotatable Bonds 254.0

Heavy Atoms 544.0

Ring Count 11.0

Amide Bonds 80.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384187 VERIFIED: YES

Provenance & Taxonomy

OrganismGalleria mellonella [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetC. fructus

RECORD: Rec_0405360 VERIFIED: YES