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MYP_130957
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Basic Information
Nigrocin-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C144H256N40O44S3
Standard
Sequence
GLLDSIKGMAISAGKGALQNLLKVASCKLDKTC
Physicochemical Analysis
3348.01 Da
9.24
2.74
2.50
0.0830
0.36
0.51
0.13
15.88
115.45
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1366.32
-14.75
49.0
50.0
120.0
231.0
0.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0200476 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID11682065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11682065/
RECORD: Rec_0209136 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperDADP: the database of anuran defense peptides PMID22467909 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22467909/
RECORD: Rec_0237258 VERIFIED: YES
Provenance & Taxonomy
Pelophylax nigromaculatus [Animal]
Nigrocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Salmonella typhimurium
22.5 μg/mL
MIC
PaperPubMed PMID: 11682065 PMID11682065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11682065/
RECORD: Rec_0266241 VERIFIED: NO
Provenance & Taxonomy
Rana nigromaculata [Animal]; Pelophylax nigromaculatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0268923 VERIFIED: YES
Provenance & Taxonomy
Rana nigromaculata [Animal]
Nigrocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Serratia marcescens
PMID11682065 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11682065/
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