Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length156 amino acids

Chemical FormulaC776H1241N221O225S5

DescriptionStandard

        MKLDKNVQRKAFLDMIAYSEGTDNGRQPTKDRGYDVIVGGKLFSDYSKHPGVYVKLNAKLTSSAAGRYQVLEKFAKHYMKQLGLPDFGPASQDNIALQLIRECKALADIDEGRIHEAIRKCRSRWASLPGAGYGQHEQKIEKLIEVFKKAGGVVLD
    

Molecular Weight17426.83 Da

Isoelectric Point (pI)9.37

Net Charge (pH 7.0)6.84

Net Charge (pH 7.4) 6.34

Charge Density (pH 7.0) 0.0439

GRAVY Index-0.51

Hydrophobic Moment 0.74

Boman Index-0.08

Instability Index38.99

Aliphatic Index 83.21

Aromaticity 0.0833

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 16055.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7249.74

LogP -68.25

H-bond Donors 252.0

H-bond Acceptors 241.0

Rotatable Bonds 599.0

Heavy Atoms 1227.0

Ring Count 23.0

Amide Bonds 167.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141456 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli O157 typing phage 14 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic