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MYP_130917
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Basic Information
Pelovaterin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
42 amino acids
C177H281N51O55S6
Standard
Sequence
DDTPSSRCGSGGWGPCLPIVDLLCIVHVTVGCSGGFGCCRIG
Physicochemical Analysis
4195.82 Da
5.30
-1.21
-1.55
-0.0288
0.55
0.30
0.26
22.00
83.33
0.0476
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1631.60
-20.43
63.0
61.0
128.0
289.0
7.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0072426 VERIFIED: YES
Provenance & Taxonomy
Pelodiscus sinensis [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Non-hemolytic
Pseudomonas aeruginosa
PMID15877362;18341335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15877362/
RECORD: Rec_0130035 VERIFIED: YES
Provenance & Taxonomy
Pelodiscus sinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-38; 16-32; 24-39
Bio-Activity Profile
Antimicrobial Antibacterial Host defense
PaperPDB 2JR3 structural record; NMR; chain A; residues 1-42
RECORD: Rec_0192818 VERIFIED: NO
Provenance & Taxonomy
Pelodiscus sinensis,Trionyx sinensis [Animal]
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
8-38; 16-32; 24-39
Bio-Activity Profile
Antimicrobial Antibacterial
RECORD: Rec_0201437 VERIFIED: YES
Provenance & Taxonomy
Pelodiscus sinensis [Animal]
Defensin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
42 μg/mL
EC50
PaperPubMed PMID: 15877362 | PubMed PMID: 18341335 PMID15877362;18341335 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15877362/
RECORD: Rec_0210747 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 7.1%, E 19.0%, T 33.3%, C 40.5% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-negative
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
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