Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC110H177N35O21S3

DescriptionStandard

        CRQIKIWFPNRRMKWKKC
    

Molecular Weight2422.00 Da

Isoelectric Point (pI)11.08

Net Charge (pH 7.0)6.74

Net Charge (pH 7.4) 6.50

Charge Density (pH 7.0) 0.3742

GRAVY Index-1.16

Hydrophobic Moment 0.30

Boman Index-0.46

Instability Index53.23

Aliphatic Index 43.33

Aromaticity 0.1667

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 956.77

LogP -5.01

H-bond Donors 37.0

H-bond Acceptors 31.0

Rotatable Bonds 82.0

Heavy Atoms 169.0

Ring Count 6.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0369590 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermUnknown

Other ModsN-term detail: Labeled with Biotinyl-Ahx

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetHaCat/ A549 cells

MethodCellular uptake assay

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