Peptide Database

Peptide NameBeta-defensin 128 (Beta-defensin 28) (DEFB-28) (Defensin; beta 128)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC483H787N125O130S7

DescriptionStandard

        MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
    

Molecular Weight10649.63 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)5.71

Net Charge (pH 7.4) 5.22

Charge Density (pH 7.0) 0.0614

GRAVY Index0.02

Hydrophobic Moment 0.63

Boman Index0.03

Instability Index18.76

Aliphatic Index 103.66

Aromaticity 0.0860

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4121.06

LogP -29.30

H-bond Donors 149.0

H-bond Acceptors 146.0

Rotatable Bonds 369.0

Heavy Atoms 745.0

Ring Count 13.0

Amide Bonds 96.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0113779 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyBeta-defensin; Defensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic