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MYP_130812
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Basic Information
Enzyme inhibitor EA
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C8H14N2O5
Standard
Sequence
EA
Physicochemical Analysis
218.21 Da
4.05
-1.16
-1.33
-0.5816
-0.85
0.52
-0.06
5.00
50.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-1.23
4.0
4.0
6.0
15.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0296759 VERIFIED: YES
Provenance & Taxonomy
Triticum aestivum [Plant]
ACE inhibitory peptide
4565
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
RECORD: Rec_0317767 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
10000 μM
IC50
PaperBinding of peptide substrates and inhibitors of angiotensin-converting enzyme. Importance of the COOH-terminal dipeptide sequence. PMID6243277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6243277/
RECORD: Rec_0368513 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperIdentification of Bioactive Peptides from Cereal Storage Proteins and Their Potential Role in Prevention of Chronic Diseases
RECORD: Rec_0389437 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
100 μM
IC50
RECORD: Rec_0397654 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic Alpha-glucosidase inhibitory
Alpha-glucosidase
17000.0
IC50
PaperMora L., Gonz¨¢lez-Rogel D., Heres A., Toldr¨¢ F.. Iberian dry-cured ham as a potential source of alpha-glucosidase-inhibitory peptides. J. Funct. Foods, 67, 103840, 2020.
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