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MYP_130812
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Basic Information
Enzyme inhibitor EA
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Glycosidase inhibition ▸ Alpha-glucosidase inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C8H14N2O5
Standard
Sequence
EA
Physicochemical Analysis
218.21 Da
4.05
-1.16
-1.33
-0.5816
-0.85
0.52
-0.06
5.00
50.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-1.23
4.0
4.0
6.0
15.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046873 VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
9823
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory
alpha-glucosidase
17000 μM
IC50
RECORD: Rec_0056972 VERIFIED: NO
Provenance & Taxonomy
Gallus gallus [Animal]
ACE-inhibitory peptide
9031
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperAnimal and Plant Proteins as Precursors of Peptides with ACE Inhibitory Activity – An in silico Strategy of Protein Evaluation
RECORD: Rec_0061595 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0099314 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Model sensory peptide
32630
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
PaperUmami peptides: assessment of their alleged taste properties. Z. Lebensm. Unters. Forsch., 205, 125-130, 1997
RECORD: Rec_0118646 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
10000.0
IC50
PaperCheung H.-S., Wang F.-L., Ondetti M. A., Sabo E. F., Cushman D. W.. Inhibitor of angiotensin I-converting enzyme (EC 3.4.15.1; MEROPS ID: M02-001).
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