Peptide Database

Peptide NameEndolysin (EC 3.2.1.17) (Lysis protein) (Lysozyme) (Muramidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC763H1224N206O228S7

DescriptionStandard

        MQLSRKGLDAIKFFEGLKLEAYEDSAGIPTIGYGTIRIDGKPVKMGMKIAAEQAEQYLLADVEKFVAAVNKAIKVPTSQNEFDALVSETYNIGITAMQDSTFIKRHNAGDKVGCAEAMQWWNKVTVKGKKVTSNGLKNRRRMETDIYLDSVYPK
    

Molecular Weight17155.58 Da

Isoelectric Point (pI)9.08

Net Charge (pH 7.0)3.59

Net Charge (pH 7.4) 3.25

Charge Density (pH 7.0) 0.0233

GRAVY Index-0.37

Hydrophobic Moment 0.70

Boman Index-0.02

Instability Index29.79

Aliphatic Index 81.10

Aromaticity 0.0844

Extinction Coeff. Reduced 19940.00

Extinction Coeff. Oxidized 19940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7068.39

LogP -66.84

H-bond Donors 244.0

H-bond Acceptors 240.0

Rotatable Bonds 589.0

Heavy Atoms 1204.0

Ring Count 20.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0114355 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoM_Alf5 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Cytolytic Non-hemolytic