Peptide Database

Peptide NameCPF-C1 [G1,7k; G3,13w; L10l; R11r; N15k]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length17 amino acids

Chemical FormulaC105H170N26O19

DescriptionStandard

        KFWSLLKKALRLWAKVL
    

Molecular Weight2100.64 Da

Isoelectric Point (pI)11.33

Net Charge (pH 7.0)4.76

Net Charge (pH 7.4) 4.55

Charge Density (pH 7.0) 0.2798

GRAVY Index0.41

Hydrophobic Moment 0.80

Boman Index0.10

Instability Index15.84

Aliphatic Index 143.53

Aromaticity 0.1765

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 746.71

LogP 0.54

H-bond Donors 28.0

H-bond Acceptors 24.0

Rotatable Bonds 71.0

Heavy Atoms 150.0

Ring Count 5.0

Amide Bonds 16.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409660 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermAmidation

Other ModsIntroduction of D-amino acid(s). (Look at 'Stereochemistry')

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetMRSA 023 isolated from clinics

Activity8 μg/mL

MethodMIC

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