Peptide Database

Peptide NameMra30a

Function Ontology

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Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC135H221N35O41S6

DescriptionStandard

        GSIPCGEGCVFIPCISSIVGCSCKSKVCYKN
    

Molecular Weight3182.80 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0548

GRAVY Index0.63

Hydrophobic Moment 0.37

Boman Index0.23

Instability Index6.60

Aliphatic Index 78.39

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1198.57

LogP -14.51

H-bond Donors 47.0

H-bond Acceptors 49.0

Rotatable Bonds 102.0

Heavy Atoms 217.0

Ring Count 4.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036863 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

-

RECORD: Rec_0353838 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)