MYP_130721
Fusaricidin C
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Antimicrobial
▸
Antifungal
Standard
6 amino acids
C29H45N7O11
Standard
TVYTNA
667.71 Da
5.18
-0.60
-0.79
-0.1005
-0.03
0.30
0.18
-43.43
65.00
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
312.60
-3.92
11.0
11.0
18.0
47.0
1.0
6.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0143562
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Asn5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
Inactive: Escherichia coli NIHJ, Klebsiella pneumoniae KC-1, Pseudomonas aeruginosa IFO 3445, S.marcescens IFO 3736, Candida albicans IFO 1594, S.cerevisiae HUT 7099
>100 μg/mL
MIC
RECORD: Rec_0277801
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Asn5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
fungi Fusarium oxysporum HF8801, Fusarium oxysporum HF8835, A. niger HUT 2016, A. oryzae 1FO 4214, and P. thomii
1.56-3.12 μg/mL
MIC
RECORD: Rec_0336855
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
RECORD: Rec_0347320
VERIFIED: YES
Provenance & Taxonomy
Paenibacillus polymyxa [Bacterium]; Bacteria [Bacterium]
1405; 2
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0372593
VERIFIED: YES
Provenance & Taxonomy
Bacillus polymyxa [Bacterium]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
mixed L/D amino-acid peptide [Mixed]
Lipidation
Esterification
The carboxylic end of Ala6 forms an ester bond with the hydroxyl group of T1. Val2, Asn5, Ala6 are D-amino acids and Thr4 is a D-allo-Thr. In addition, the N-terminus NH is lipidated with 15-guanidino-3-hydroxypentadecanoic acid (GHPD). Refer to the article for additional physical properties
Bio-Activity Profile
Antimicrobial
Antifungal
Gram-positive Staphylococcus aureus FDA 209p, Staphylococcus aureus Smith, Micrococcus luteus IFO 3333, Bacillus subtilis ATCC 6633
<0.78-3.12 μg/mL
MIC
Showing 5 records on this page · Page 1 of 2